Health News Report

Wednesday, November 13, 2019

Regular use of prescription drugs for pain and sleep increases frailty risk by 95 percent


Researchers from the Oregon Research Institute (ORI) and Florida Atlantic University (FAU) are the first to demonstrate statistically significant links between self-reported regular use of prescription drugs for pain and/or sleep, and longitudinal risk of frailty in adults ages 65 and older. Frailty consists of deficits in a variety of functional measures, and is a reliable predictor of loss of independence, increased use of health care resources, and mortality. The possible implications of current research findings are especially serious given that it is common for older Americans to use two or more prescription drugs at the same time and many of these prescription drugs are for pain and sleep, including analgesics and sedatives.
Results, published online in the Journal of the American Geriatric Society, estimate long-term frailty risks and rank the long-term risks of two classes of prescription drugs. Researchers found over eight years of follow-up, those who self-reported regular use of prescription drugs for pain and sleep had a 95 percent increased risk of frailty compared to those who did not report regular use of these drugs. For regular prescription drug use for pain only or for sleep only, the increased risks were 58 percent and 35 percent, respectively.
Co-authors Gulcan Cil, Ph.D., associate scientist, ORI, Juyoung Park, Ph.D., associate professor in FAU's Phyllis and Harvey Sandler School of Social Work within the College for Design and Social Inquiry, and senior scientist Andrew Bergen, Ph.D., ORI, analyzed data from the Health & Retirement Study (HRS), a nationally representative longitudinal cohort of older Americans. For their analysis, they selected a large cohort (N=7,201) of community-living non-frail older adults (age 65 to 104, mean 72, median 70) from the HRS. Analyses were adjusted for demographics and other drug use.
"Co-use of multiple prescription medications is a growing phenomenon, especially among older adults," said Park. "Geriatric medicine societies, including the American Geriatric Society, have developed guidelines to help prescribers avoid potentially inappropriate prescribing or PIP, which requires assessment of several types of PIP, including the benefits and risks associated with certain drug classes."
"Our study shows that regular self-reported use and co?use of prescription drugs for pain and for sleep are significantly associated with increased incidence of frailty," said Bergen. "We recommend further research to estimate the frailty risk of pain and sleep measures and of prescription pain and sleep drugs."
The HRS dataset used by the researchers is sponsored by the National Institute on Aging (NIA) of the National Institutes of Health and the Social Security Administration (SSA) and is conducted by the University of Michigan. RAND HRS data products used in this study are produced by RAND Center for the Study of Aging with funding from the NIA and SSA.
Park will present this work at the Gerontological Society of America Annual Scientific Meeting (geron.org/2019) on Nov. 16 in Austin, Texas.
###
About the Oregon Research Institute
Founded in 1960, Oregon Research Institute (ORI) is a charitable 501(c) 3 research center, dedicated entirely to understanding human behavior and improving the quality of human life. Funded by research grants from the National Institutes of Health and by the United States Department of Education, ORI scientists study such topics as childhood obesity and behavioral problems, promoting health across the age span, preventing and treating teen substance use and abuse, and understanding and preventing eating disorders. Emerging areas include genetics, opioid addiction, Alzheimer's disease, and health economics. See http://www.ori.org.
About Florida Atlantic University:
Florida Atlantic University, established in 1961, officially opened its doors in 1964 as the fifth public university in Florida. Today, the University, with an annual economic impact of $6.3 billion, serves more than 30,000 undergraduate and graduate students at sites throughout its six-county service region in southeast Florida. FAU's world-class teaching and research faculty serves students through 10 colleges: the Dorothy F. Schmidt College of Arts and Letters, the College of Business, the College for Design and Social Inquiry, the College of Education, the College of Engineering and Computer Science, the Graduate College, the Harriet L. Wilkes Honors College, the Charles E. Schmidt College of Medicine, the Christine E. Lynn College of Nursing and the Charles E. Schmidt College of Science. FAU is ranked as a High Research Activity institution by the Carnegie Foundation for the Advancement of Teaching. The University is placing special focus on the rapid development of critical areas that form the basis of its strategic plan: Healthy aging, biotech, coastal and marine issues, neuroscience, regenerative medicine, informatics, lifespan and the environment. These areas provide opportunities for faculty and students to build upon FAU's existing strengths in research and scholarship. For more information, visit http://www.fau.edu.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.
Media Contact
Kathryn Madden
5414842123
Kathryn@ori.org
Juyoung Park
4434169772
jpark14@fau.edu

More on this News Release

Regular use of prescription drugs for pain and sleep increases frailty risk by 95 percent

Oregon Research Institute
Journal
Journal of American Geriatrics Society
Meeting
Gerontological Society of American 2019 Annual Scientific Meeting

Keywords

  • AGING
  • MORTALITY/LONGEVITY
  • PAIN
  • SLEEP/SLEEP DISORDERS
  • SOCIAL/BEHAVIORAL SCIENCE

Original Source

https://doi.org/10.1111/jgs.16214

Related Journal Article

http://dx.doi.org/10.1111/jgs.2019.16214

More in Social & Behavior

  • Regular use of prescription drugs for pain and sleep increases frailty risk by 95 percent Oregon Research Institute
  • First look at thermostat wars suggests women may be losing these battles Ohio State University
  • Puberty may offer window to reset effects of early deprived care on stress-response system University of Minnesota
  • Cholesterol, fat profiles at birth linked to psychological health at age 5 Association for Psychological Science
View all in Social & Behavior 

Trending News Releases

  • Extinct giant ape directly linked to the living orangutan University of Copenhagen The Faculty of Health and Medical Sciences
  • Distant worlds under many suns Friedrich-Schiller-Universitaet Jena
  • Taller people have increased risk for developing atrial fibrillation University of Pennsylvania School of Medicine
  • Discovery: New biomarker for cancer stem cells University of Houston
View all latest news releases 

EurekAlert! The Global Source for Science News
AAAS - American Association for the Advancement of Science
Copyright © 2019 by the American Association for the Advancement of Science (AAAS)
  • Latest News Releases RSS Feed
  • All EurekAlert! RSS Feeds
  • @EurekAlert
  • facebook.com/EurekAlert
  • Help / FAQ
  • Disclaimer
  • Privacy Policy
  • Terms & Conditions
  • Contact EurekAlert!
Posted by Jonathan Kantrowitz at 2:46 PM

No comments:

Post a Comment

Newer Post Older Post Home
View mobile version
Subscribe to: Post Comments (Atom)

About Me

My photo
Jonathan Kantrowitz
View my complete profile

Blog Archive

  • ►  2025 (121)
    • ►  May (21)
    • ►  April (28)
    • ►  March (39)
    • ►  February (15)
    • ►  January (18)
  • ►  2024 (352)
    • ►  December (35)
    • ►  November (38)
    • ►  October (28)
    • ►  September (21)
    • ►  August (38)
    • ►  July (27)
    • ►  June (38)
    • ►  May (22)
    • ►  April (15)
    • ►  March (35)
    • ►  February (35)
    • ►  January (20)
  • ►  2023 (245)
    • ►  December (19)
    • ►  November (25)
    • ►  October (17)
    • ►  September (16)
    • ►  August (21)
    • ►  July (29)
    • ►  June (18)
    • ►  May (20)
    • ►  April (16)
    • ►  March (22)
    • ►  February (16)
    • ►  January (26)
  • ►  2022 (395)
    • ►  December (23)
    • ►  November (21)
    • ►  October (21)
    • ►  September (38)
    • ►  August (35)
    • ►  July (35)
    • ►  June (40)
    • ►  May (26)
    • ►  April (22)
    • ►  March (52)
    • ►  February (38)
    • ►  January (44)
  • ►  2021 (589)
    • ►  December (31)
    • ►  November (42)
    • ►  October (68)
    • ►  September (53)
    • ►  August (58)
    • ►  July (35)
    • ►  June (50)
    • ►  May (57)
    • ►  April (35)
    • ►  March (66)
    • ►  February (61)
    • ►  January (33)
  • ►  2020 (506)
    • ►  December (29)
    • ►  November (37)
    • ►  October (33)
    • ►  September (43)
    • ►  August (35)
    • ►  July (61)
    • ►  June (56)
    • ►  May (35)
    • ►  April (33)
    • ►  March (56)
    • ►  February (44)
    • ►  January (44)
  • ▼  2019 (824)
    • ►  December (46)
    • ▼  November (36)
      • Analysis of US life expectancy
      • Playing board games may help protect thinking skil...
      • Aerobic exercise and heart-healthy diet may slow d...
      • Salt, sugar, frying in oil bad; Ketogenic diet good
      • Cannabis reduces headache and migraine pain by nea...
      • Extra virgin olive oil staves off multiple forms o...
      • Lack of sleep may explain why poor people get more...
      • HPV vaccines & vaccine schedules in adolescent gir...
      • Diet pills, laxatives used for weight control link...
      • Science underestimated dangerous effects of sleep ...
      • Legumes boost heart health, according to new revie...
      • Sesame allergy common among children with food all...
      • Healthful diet tied to lower risk of hearing loss
      • Latest Health Research
      • Statins not associated with memory or cognition de...
      • High-protein diets may harm your kidneys
      • Nearly half of 50- to 64-year-olds think they're...
      • Unhealthy habits can start young: Infants, toddler...
      • Improved fitness can mean living longer without de...
      • Take a yoga class and depression, anxiety improve
      • Fracture risk for patients taking multiple medicat...
      • Regular use of prescription drugs for pain and sle...
      • Too much ultra-processed foods linked to lower hea...
      • Evening eating linked to poorer heart health for w...
      • Folic acid supplementation may positively impact n...
      • Insomnia symptoms linked to increased risk of stro...
      • Shortened sleep may negatively affect women's bone...
      • Study: Actually, potted plants don't improve indoo...
      • The reproductive function of the clitoris
      • Association between physical activity, lower risk ...
      • Physical activity may protect against new episodes...
      • Links between prescription medications and risk fo...
      • Is physical activity always good for the heart?
      • Fish oil supplements have no effect on anxiety and...
      • Interval walking training improves fitness and hea...
      • Being physically active can lower older adults' ri...
    • ►  October (63)
    • ►  September (56)
    • ►  August (63)
    • ►  July (61)
    • ►  June (90)
    • ►  May (78)
    • ►  April (86)
    • ►  March (82)
    • ►  February (78)
    • ►  January (85)
  • ►  2018 (772)
    • ►  December (70)
    • ►  November (90)
    • ►  October (75)
    • ►  September (44)
    • ►  August (78)
    • ►  July (69)
    • ►  June (63)
    • ►  May (53)
    • ►  April (69)
    • ►  March (53)
    • ►  February (34)
    • ►  January (74)
  • ►  2017 (741)
    • ►  December (44)
    • ►  November (92)
    • ►  October (55)
    • ►  September (56)
    • ►  August (70)
    • ►  July (49)
    • ►  June (79)
    • ►  May (65)
    • ►  April (47)
    • ►  March (57)
    • ►  February (71)
    • ►  January (56)
  • ►  2016 (487)
    • ►  December (38)
    • ►  November (56)
    • ►  October (72)
    • ►  September (20)
    • ►  August (38)
    • ►  July (36)
    • ►  June (27)
    • ►  May (51)
    • ►  April (37)
    • ►  March (39)
    • ►  February (35)
    • ►  January (38)
  • ►  2015 (499)
    • ►  December (34)
    • ►  November (37)
    • ►  October (31)
    • ►  September (43)
    • ►  August (38)
    • ►  July (34)
    • ►  June (47)
    • ►  May (43)
    • ►  April (52)
    • ►  March (61)
    • ►  February (36)
    • ►  January (43)
  • ►  2014 (492)
    • ►  December (57)
    • ►  November (35)
    • ►  October (46)
    • ►  September (52)
    • ►  August (27)
    • ►  July (23)
    • ►  June (35)
    • ►  May (47)
    • ►  April (51)
    • ►  March (39)
    • ►  February (44)
    • ►  January (36)
  • ►  2013 (367)
    • ►  December (24)
    • ►  November (33)
    • ►  October (41)
    • ►  September (30)
    • ►  August (22)
    • ►  July (24)
    • ►  June (16)
    • ►  May (41)
    • ►  April (39)
    • ►  March (33)
    • ►  February (35)
    • ►  January (29)
  • ►  2012 (480)
    • ►  December (26)
    • ►  November (53)
    • ►  October (60)
    • ►  September (26)
    • ►  August (34)
    • ►  July (23)
    • ►  June (45)
    • ►  May (44)
    • ►  April (45)
    • ►  March (54)
    • ►  February (34)
    • ►  January (36)
  • ►  2011 (466)
    • ►  December (27)
    • ►  November (36)
    • ►  October (37)
    • ►  September (37)
    • ►  August (55)
    • ►  July (32)
    • ►  June (41)
    • ►  May (52)
    • ►  April (43)
    • ►  March (33)
    • ►  February (32)
    • ►  January (41)
  • ►  2010 (466)
    • ►  December (31)
    • ►  November (34)
    • ►  October (24)
    • ►  September (34)
    • ►  August (36)
    • ►  July (34)
    • ►  June (55)
    • ►  May (42)
    • ►  April (55)
    • ►  March (42)
    • ►  February (32)
    • ►  January (47)
  • ►  2009 (256)
    • ►  December (28)
    • ►  November (38)
    • ►  October (24)
    • ►  September (38)
    • ►  August (34)
    • ►  July (25)
    • ►  June (22)
    • ►  May (24)
    • ►  April (10)
    • ►  March (3)
    • ►  February (4)
    • ►  January (6)
  • ►  2008 (20)
    • ►  December (6)
    • ►  November (7)
    • ►  October (5)
    • ►  July (2)
  • ►  2007 (336)
    • ►  October (2)
    • ►  August (6)
    • ►  July (23)
    • ►  June (69)
    • ►  May (72)
    • ►  April (46)
    • ►  March (44)
    • ►  February (38)
    • ►  January (36)
  • ►  2006 (48)
    • ►  December (43)
    • ►  November (5)
Ethereal theme. Powered by Blogger.