Thursday, July 30, 2026

Nearly 1 in 3 U.S. adults with high blood pressure may need medication

Nearly 23 million Americans with blood pressure 130/80 mm Hg or higher may be eligible for blood-pressure-lowering medications based on the 2025 American Heart Association/American College of Cardiology guideline, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed scientific journal of the American Heart Association.

The 2025 American Heart Association/American College of Cardiology High Blood Pressure guideline advises lifestyle changes — eating a healthy diet, managing weight, getting regular physical activity and reducing salt and alcohol — as a key part of treatment for high blood pressure, with medication prescribed if appropriate. The guideline also suggests healthcare professionals use the American Heart Association’s PREVENTTM (Predicting Risk of cardiovascular disease EVENTs) risk equations to calculate 10-year cardiovascular disease risk among adults (ages 30-79 without known cardiovascular disease) with high blood pressure who do not have established cardiovascular disease.

This study is one of the first detailed assessments of the 2025 guideline on high blood pressure and updated cardiovascular disease risk estimates using the PREVENT risk equations.

“Through this study, our goal was to understand how many people may qualify for treatment according to the updated recommendations in the guideline and estimate how many deaths from any cause and from cardiovascular disease may be prevented in the long term if the guideline recommendations were applied and untreated patients received care that included medication,” said study lead author Mustafa Al-Jarshawi, M.B.Ch.B., M.Sc., MRCPUK, PgCert, an academic clinical fellow in cardiology, member of the Cardiovascular Research Group at the Centre for Prognosis Research at Keele University in the United Kingdom and honorary research fellow at the Centre for Health Informatics, University of Manchester.

Researchers examined links between blood pressure treatments and rates of deaths from all causes and from cardiovascular conditions. Their analysis predicted how many lives may be saved if treatment plans outlined in the 2025 guideline were prescribed.

The data analysis found:

  • 81 million U.S. adults had a diagnosis of high blood pressure. Of these, 22.8 million (28%) were guideline-eligible for therapy based on a blood pressure reading of 130/80 mm Hg or higher. 13.1 million (57%) adults were already receiving treatment for high blood pressure, while 9.7 million (43%) remained untreated. Please note: The blood pressure readings were measured during one office visit for the National Health and Nutrition Examination Survey (NHANES) collected between 2009 and 2018. The current guideline advises taking multiple readings during multiple office visits. This is an important study limitation.
  • The analysis estimates that, among eligible adults, receiving blood pressure-lowering medications was associated with a 23% lower risk of dying from any cause and a 50% lower risk of dying from heart-related issues. This was compared to eligible adults who do not receive treatment.
  • If treatment with medications was extended to all untreated but eligible adults, the analysis estimates approximately 200,000 all-cause deaths and 162,000 cardiovascular deaths may be prevented during the next decade.
  • People eligible for high blood pressure treatment with medication who would benefit most were older, with an average age of 66, and had more health conditions, including diabetes, chronic kidney disease and other cardiovascular disease risk factors.

“What stood out most was the size of the treatment gap — more than 40% of people who were clearly eligible under the new guideline were not receiving treatment, as well as the scale of the potential benefit,” Al-Jarshawi said.

“Lifestyle modification remains the foundation of high blood pressure management. Maintaining a healthy weight, consuming a heart-healthy diet, reducing sodium intake, increasing physical activity, getting enough sleep, managing stress and limiting alcohol can meaningfully lower blood pressure and overall cardiovascular risk,” said study senior author Mamas A. Mamas, M.D, DPhil., Professor of Cardiology at Keele University and Honorary Professor of Population Health at the University of Manchester. “For many people, especially those with blood pressure under 140/90 mm Hg and no history of heart disease, stroke, chronic kidney disease or diabetes, lifestyle changes can be enough at first. If your 10-year risk of heart disease is low, with a PREVENT score under 7.5%, maintaining a healthy lifestyle can help you delay or avoid needing medication. Even if you do need medication to lower blood pressure, making lifestyle changes is important for effective treatment and overall health.”

“The 2025 guideline emphasizes a personalized approach to managing high blood pressure by considering blood pressure levels plus 10-year and 30-year overall cardiovascular disease risk. The American Heart Association’s PREVENT risk equations help to identify individuals who could benefit from treatment before a major cardiac event,” said Chair of the American Heart Association’s 2025 guideline writing committee Daniel W. Jones, M.D., FAHA.

“Controlling blood pressure is crucial for long-term health. While lifestyle changes are the foundation for better overall health, people with high blood pressure and higher risk for cardiovascular disease may also need medication to reduce the risk of serious complications from untreated high blood pressure. Healthcare professionals should assess overall cardiovascular risk and work together with their patients to combine lifestyle strategies and medication for optimal blood pressure control.” Jones, who was not involved in this study, is a past volunteer president of the American Heart Association (2007-2008) and is dean and professor emeritus of the University of Mississippi School of Medicine in Jackson, Mississippi.

Study details, background, design and limitations:

  • The study had 53% male and 47% female participants, 9.4% had chronic kidney disease, 17 % had diabetes, 47% had dyslipidemia and 15% were current smokers.
  • The participants self-identified as 70% white adults, 12% Black adults, 7.2% Mexican American adults, 5.8% multiracial adults and 4.2% other Hispanic adults.
  • Study limitations include that researchers did not randomly assign the treatment, which means other unmeasured factors may have influenced treatment and the results. Since blood pressure was measured during a single NHANES visit and researchers examined treatment at only one point in time, the study could not capture how patients’ medication use or treatment routines may have changed over time as they worked with their healthcare teams.

 

Common antihistamines provide little meaningful benefit for eczema

 

It’s typical for someone looking for relief from dry, itchy, red and irritated skin – also known as eczema or atopic dermatitis – to turn to common allergy medications called antihistamines. New research from McMaster University, however, has found that these commonly used medications don’t make a meaningful difference in improving symptoms, and for some of the most commonly used antihistamines, they can cause harm.


Oral antihistamines are a common staple in households around the globe, with many available without a prescription. The belief is these medications will help temper down itching and disruptions to sleep caused by eczema, but clinical practice and guidelines vary in recommending for or against the potential benefits due to lack of clear evidence.

As detailed in the BMJ on July 29, 2026, researchers found that oral antihistamines do not importantly improve the outcomes that matter most in controlling eczema, and can increase the risk of cognitive impairment. To come to this conclusion, a systematic review of 47 randomized trials consisting of 6,230 children and adults with mild to severe eczema was conducted – the most comprehensive analysis to date on the topic.

“Eczema care increasingly focuses on controlling skin and immune inflammation with moisturizers, topical anti-inflammatory treatments, and whole-body treatments like phototherapy, biologics, and oral JAK inhibitors. That makes it important to know whether antihistamines add important benefit or mostly add treatment burden and harm,” says senior author Derek Chu, associate professor with McMaster’s Department of Medicine, Canadian Institutes of Health Research Chair in Allergy, and Lead of Canada’s Allergy Clinical Trials Network.

The review looked at two categories of medications: modern, second-generation antihistamines and older, first-generation antihistamines. The study found that second-generation medications – commonly known under brand names such as Reactine, Claritin, Aerius, Allegra, Rupall, and Blexten – produced small changes in eczema severity and itch, but that relief fell short of what patients and their clinicians would consider as an important improvement.

First-generation antihistamines – commonly found under brand names such as Benadryl, Chlor-Tripolon and Polaramine – produced no noticeable improvement. These older medications, however, likely increase cognitive impairment, such as drowsiness, confusion, slowed thinking, or impaired school or work performance. Such impairments are increasingly recognized to last into the days after use. Among newer second-generation antihistamines, cognitive effects were much lower and differed by drug (bilastine, desloratadine, and fexofenadine being least sedating).

“The findings support moving away from routine antihistamine use in atopic dermatitis care and toward treatments that are more effective, less likely to cause harm, and are more certain to control eczema inflammation. This may also help keep eczema control as simple and straightforward as possible, with patients focusing on high-value treatments,” says Chu, who holds a joint appointment with McMaster’s Department of Health Research Methods, Evidence and Impact.

Researchers stress that oral antihistamines have a place in treating allergic conditions such as hay fever, seasonal allergies and hives.

The work was commissioned by the American Academy of Allergy, Asthma & Immunology and the American College of Allergy, Asthma and Immunology through the Joint Task Force on Practice Parameters for the living atopic dermatitis guidelines.

The study used the McMaster-developed grading of recommendations assessment, development and evaluation (GRADE), a leading global system for rating the certainty of evidence and translating evidence into clinical recommendations.

Aspects of the study were conducted with The Research Institute of St. Joe's Hamilton.

This McMaster-led research involved partners from Harvard T.H. Chan School of Public Health, Children's Hospital of Philadelphia/University of Pennsylvania, Boston Children's Hospital, National Jewish Health/University of Colorado, UMass Chan Medical School, Arizona State University, George Washington University, Northwestern University, University of Saskatchewan, Icahn School of Medicine at Mount Sinai, University of Rochester, University of Florida, Children's Hospital Los Angeles/USC, Lakehead University, and Tufts University.

People with lived experience and advocacy partners including the Asthma and Allergy Foundation of America, Global Parents for Eczema Research, National Eczema Association, and Allergy & Asthma Network were also involved.


Wednesday, July 29, 2026

For long-term health, diet quality matters more than food processing level

 What makes a diet healthy—or not? According to a new study, nutritional quality matters more than processing level when it comes to long-term health.

The study of over 200,000 people found that the overall quality of a person’s diet was strongly associated with their risk of heart disease, type 2 diabetes, and death. However, these associations did not appear to substantially differ based on food processing levels.

“While many ultra-processed foods tend to be of poor nutritional quality and should generally be limited or avoided, processing itself is not inherently harmful,” said Xiaowen Wang, PhD, a postdoctoral research fellow in the Department of Nutrition at Harvard T. H. Chan School of Public Health. Based on the study results, she said individuals should “focus on what you’re eating overall, not just whether it’s processed. A healthy plant-based diet rich in whole grains, fruits, vegetables, nuts, legumes and healthy plant oils is beneficial, even if it includes some processed foods.”

Wang will present the findings at NUTRITION 2026, the flagship annual meeting of the American Society for Nutrition, held July 25–28 in National Harbor, Maryland, just outside Washington, D.C.

The nutritional quality of a person’s diet and the amount of ultra-processed foods they consume are often intertwined. Many ultra-processed foods are high in added sugars, sodium and refined carbohydrates, so eating a lot of these foods is associated with poor dietary quality. On the other hand, ultra-processed foods like fortified breakfast cereals, whole grain products, canned beans, or plant-based dairy can still provide important nutrients, fiber, antioxidants and other beneficial compounds, contributing to a healthy diet.

For the study, researchers sought to separate overall diet quality from the level of food processing. Using data from three studies that collectively followed over 200,000 U.S. adults from the 1980s through the 2020s, they used a framework known as the plant-based diet index to assess the degree to which each participant emphasized plant versus animal food products in their diet, the overall quality or healthfulness of their diet, and their consumption of plant-based foods across a wide spectrum of processing levels. The study was not limited to vegans or vegetarians; however, to enable consistent comparisons, the analysis focused on the plant-derived components of participants’ diets rather than animal-derived foods.

After assessing each participant’s overall diet and using the Nova classification system to categorize the processing level of the foods they consumed, researchers grouped participants according to their plant-based eating habits:

  • Healthy/ultra-processed (for example, whole grain breakfast cereal with fortified plant-based milk, plant-based yogurt, whole-grain bread, and canned fruit);
  • Healthy/minimally-processed (for example, oatmeal with fresh fruit and nuts, quinoa and vegetable salad with olive oil, and homemade lentil soup);
  • Unhealthy/ultra-processed (for example, fast food meals, French fries, soda, packaged desserts, and refined snacks); and
  • Unhealthy/minimally-processed (for example, white rice, fruit juice, potatoes, and homemade desserts made with refined flour and sugar).

About half of the study participants eventually died or developed heart disease or type 2 diabetes. According to the results, the risk of these outcomes varied significantly depending on overall diet quality: healthy diets were associated with lower risk, while unhealthy diets were associated with higher risk. Within each category, however, the risks were almost identical regardless of whether the diet was ultra-processed or minimally-processed.

The results call into question the use of processing level as a key indicator of healthy eating. Since the Nova classification does not take into account the nutritional value of foods, healthy foods can be classified as ultra-processed while minimally-processed foods can still be unhealthy. 

“Advising people to universally ‘avoid ultra-processed foods’ can lead to lower diet quality since healthy ultra-processed foods are beneficial and unhealthy minimally-processed foods are detrimental,” said Wang. “People should prioritize the quality of foods rather than focusing solely on the level of processing. Aim for more nutrient-dense, high-quality foods to help lower your risk of chronic diseases.”

Based on the findings, she suggested that dietary guidelines should continue to promote established high-quality diets, like the Mediterranean or healthy plant-based diets, rather than focusing on processing level. She noted that encouraging food manufacturers to improve the nutritional content of packaged foods could also help to make following a healthy plant-based diet more convenient and accessible.

The consumption of ultra-processed foods by fathers may influence their babies..

 

 birth weight and body measurements


A study conducted at the University of São Paulo reinforces the importance of including fathers in health and family planning guidance.

A father’s diet can affect his children’s health and body composition before they are even conceived. A study of 43 triads of fathers, mothers, and newborns treated in the public healthcare system of Ribeirão Preto in the state of São Paulo, Brazil, demonstrated this. The analysis revealed that the greater the consumption of ultra-processed foods by the fathers, the higher the birth weight and the greater the accumulation of fat in the baby’s thighs and suprailiac region (commonly known as “love handles”). High birth weight and elevated body fat early in life are risk factors for cardiometabolic diseases in adulthood.

“Maternal nutrition and health before, during, and after the baby’s birth have always received attention, but little is said about the role of the father’s diet. Our study shows that it also matters a great deal for the baby’s health," says Daniela Sartorelli, a professor at the Ribeirão Preto School of Medicine at the University of São Paulo (FMRP-USP) who coordinated the study published in the journal Nutrition Research

The study is the first to demonstrate an association between fathers’ consumption of ultra-processed foods and the body composition of newborns. So-called ultra-processed foods are industrial formulations mostly made of food-extracted substances and synthetic chemical additives; the presence of whole foods in the composition of items such as packaged snacks, filled cookies or soft drinks is either scarce or non-existing.

The researchers’ hypothesis is that consuming ultra-processed foods negatively impacts sperm formation, which occurs prior to conception. “Diets rich in ultra-processed foods can create a pro-inflammatory environment in the body, affecting sperm quality and altering the expression of genes that will be passed on to the baby. This process is known as epigenetics. Gene activity can be ‘activated’ or ‘deactivated’ depending on the father’s dietary habits,” explains Mariana Rinaldi Carvalho, a FAPESP doctoral scholarship recipient and co-author of the study.

One of the genes mentioned in the study is IGF-II, which is responsible for fetal growth and is inherited exclusively from the father. “Previous studies have shown that a father’s dietary habits can biochemically modify this gene in sperm through a process called methylation [the addition of a methyl group], thereby influencing fetal development,” says the researcher.

The study is part of a larger project supported by FAPESP that investigates how the diets of mothers and fathers influence the health of newborns.

According to the results, fathers’ consumption of ultra-processed foods was associated with higher birth weights, while the effect of mothers’ consumption was the opposite. Consuming these foods early in pregnancy (up to the 16th week) was associated with lower birth weight, shorter height, and smaller head circumference at birth.

“We believe that the impact of maternal consumption of ultra-processed foods on the baby’s birth weight and body measurements may be related to placental development, which depends on many nutrients. Ultra-processed foods are, in fact, nutrient-poor,” Carvalho assesses.

Health predictor

A baby’s birth weight is considered an important predictor of health in both childhood and adulthood. In addition to an increased risk of death, numerous studies have shown that babies born with low (or high) birth weights may develop noncommunicable diseases later in life, such as cardiovascular disease, type 2 diabetes, and certain types of cancer.

“Although the study didn’t find an increase in total body fat, only fat accumulation in certain regions of the baby’s body, the results suggest that the quality of the father’s diet may also influence fetal development. This is important because, on average, ultra-processed foods accounted for 30% of the total energy consumed by the fathers whose diets were analyzed in the study, particularly processed meats, sugary drinks, and cookies,” Sartorelli notes.

In a previous study, the same team of researchers observed that overweight fathers tended to have babies with lower birth weights. However, by specifically analyzing diet quality, they demonstrated that it isn’t only the father’s weight that matters but also what he eats (read more at agencia.fapesp.br/53400). 

“With these two studies, we’ve shown that it isn’t just a matter of whether the father is overweight. The quality of the father’s diet before conception has a significant impact on the baby’s health,” says Sartorelli. 

Although the sample size was small, with only 43 families, the study is a pioneering effort to investigate the impact of ultra-processed foods on paternal and neonatal health. “The results pave the way for larger studies and reinforce the need to include men, not just women, in family planning guidance,” says Sartorelli. 


Tuesday, July 28, 2026

Omega-3 fatty acids are highest in milk labeled as organic grass-fed

  When you pick up a gallon of milk at the store, the nutrients it contains may depend on both what’s on the label and the time of year. A new study reports that omega-3 fatty acids are highest in milk labeled as organic grass-fed and lowest in conventionally-produced milk. Other fatty acids varied by dairy production method and season.

“These findings contribute to a greater understanding of the role that production systems may play in determining the nutritional composition and potential nutritional value of milk,” said Emily Youngmark, MS, a PhD student at the University of Vermont. “The observed differences in fatty acid composition may represent one factor consumers consider when choosing milk products.”

Youngmark will present the findings at NUTRITION 2026, the flagship annual meeting of the American Society for Nutrition, held July 25-28 in National Harbor, Maryland, just outside Washington, D.C. Youngmark conducted the study with Jana Kraft, PhD, associate professor at the University of Vermont.

U.S. consumers can often find a large array of options in the dairy aisle, but the differences among them are not always clear. Since products marketed as organic, grass-fed or pasture-based are often sold at premium prices and promoted as having nutritional advantages, the researchers sought to find out whether production systems actually influence milk composition.

Over the course of a year, the team collected over 300 samples of milk sold by retailers across Vermont and New York. Using information from dairy producers and product labels, they categorized each sample as conventional (63 samples), organic (111), organic grass-fed (91) or non-organic, pasture-based (40).

On average across all seasons, organic grass-fed milk contained significantly more omega-3 fatty acids than all other milks, providing 88 milligrams per serving compared with 25 mg/serving in conventionally-produced milk. By contrast, omega-6 fatty acids were highest in conventionally-produced milk, which contained 166 mg/serving versus 92 mg/serving in organic grass-fed milk. While both types of fatty acids are part of a healthy diet, experts recommend focusing on increasing omega-3 intake, which is linked with a reduced risk of heart disease, type 2 diabetes and inflammation.

The fatty acid composition of non-organic, pasture-based milk was generally comparable to organic milk, with some seasonal variation. In general, it appears that cows with more access to pasture and fresh forage produce milk with more beneficial fatty acids. Variation in nutritional composition throughout the year likely results from seasonal differences in forage quality.

Although the results revealed significant differences in fatty acid composition among milk samples, researchers noted that the health implications of these differences remain uncertain. Further studies would be needed to determine whether regularly consuming certain types of milk leads to measurable improvements in health outcomes.

“It is important to put these findings in perspective. While the differences we observed may be nutritionally relevant, they are unlikely to produce major health effects on their own. Rather, the fatty acid composition of organic grass-fed milk may contribute as one component of an overall healthy dietary pattern and lifestyle,” said Youngmark.

Conventional milk has no formal definition but generally refers to milk produced from intensively managed dairy systems. Certified organic milk is produced under federally regulated standards that prohibit the use of pesticides, genetically modified feeds and most synthetic additives and require pasture access for at least 120 days per year. Organic grass-fed certification imposes additional requirements, including pasture access for at least 160 days per year and the exclusion of grain products from feed. The term “pasture-based” can appear on both organic and non-organic milk; non-organic, pasture-based milk production systems emphasize pasture access but are not certified organic. 

A daily multivitamin may help older adults maintain functional health

 

The ability to perform everyday activities free of debilitating symptoms profoundly affects quality of life as we age. In a new study, older adults who took a daily multivitamin had significantly better measures of functional health after 3 years compared with those who took a placebo.


According to researchers, the findings suggest a daily multivitamin can help older people maintain day-to-day functioning by helping to preserve cognitive abilities, and it may also benefit blood circulation and physical stamina.

“What makes this work unique is our focus on functional health, how people actually feel and function in their daily lives—rather than just the prevention of major diseases,” said Bayu B. Bekele, PhD, a postdoctoral fellow at the Georgia Prevention Institute of the Medical College of Georgia at Augusta University. “For older adults, these findings suggest that a daily multivitamin could be a helpful, low-risk addition to a healthy lifestyle to support physical well-being as they age, although it is not a substitute for a good diet or exercise.”

The researchers analyzed data from over 16,000 people aged 60 years and older who participated in the COcoa Supplement Multivitamins Outcomes Study (COSMOS). COSMOS participants were randomly assigned to take a daily multivitamin, a cocoa extract supplement, both or neither, with placebos used for the control group and for those taking only one supplement.

After 3 years, participants taking a multivitamin had significantly better functional health than those taking a placebo based on their responses to the Kansas City Cardiomyopathy Questionnaire. The greatest differences were seen in symptom burden and clinical summary score, which reflects an average of symptom burden and physical ability scores. 

“Multivitamin use supporting heart health and overall physical function may help maintain the ability to perform everyday activities such as dressing, bathing, walking, climbing stairs, jogging or hurrying, and completing household chores. These benefits may be particularly relevant for individuals experiencing fatigue, shortness of breath or swelling in the feet, which can limit daily functioning,” said Bekele.

Cocoa extract did not significantly change functional health scores in the overall population, although it provided a significant benefit in the patients with congestive heart failure.

It is important to check with a doctor before taking any new supplements.


Is your diet driving up your cholesterol? That may depend on your gene

 

Study suggests genetic factors explain why some people see their LDL cholesterol spike on a low-carb, high-fat diet

Can a low-carb diet cause your cholesterol to skyrocket? This question has vexed researchers and influencers alike as the popularity of low-carbohydrate diets has surged, yet the evidence has remained mixed. New research suggests that the answer depends on your genes.

According to the study, the high saturated fat intake that tends to accompany a low-carb diet interacts with genetic factors in ways that can increase low-density lipoprotein (LDL) cholesterol, considered a key driver of heart disease risk. The role of genes explains why different individuals can follow the same diet but see different outcomes. 

“Our findings suggest that some individuals may be more sensitive to the LDL cholesterol-raising effects of saturated fat, particularly in the context of a low-carbohydrate diet, because of their genetic background,” said Alexa Barad, PhD, RDN, a postdoctoral scholar at Stanford University School of Medicine.

“These findings highlight that there is real heterogeneity in how people respond to diet. Dietary conversations can sometimes become overly simplified. One person may say, ‘Low-carb diets always raise LDL cholesterol,’ while another says, ‘My LDL cholesterol did not change at all.’ Our findings suggest that both experiences can be true, depending, at least in part, on the individual’s genetic makeup,” said Barad.

Previous studies have shown healthy low-carbohydrate diets can support weight loss and blood sugar control for some people, but these diets have inconsistent effects on LDL cholesterol. Researchers sought to find a way to predict who would likely benefit from a low-carb diet and who may see a dangerous spike in LDL cholesterol.

The research is based on data from DIETFITS, a randomized controlled trial in which over 600 adults followed either a healthy low-carb or healthy low-fat diet for a year. The primary study found that neither diet was superior to the other in terms of weight loss. For the new analysis, researchers assessed the relationships among genotype, saturated fat intake, diet type and change in LDL cholesterol from baseline to 6 months in 431 DIETFITS participants with available genetic data.

Among participants following the low-carb diet, the results showed that those with a genetic predisposition toward elevated LDL cholesterol were more likely to see their cholesterol rise. The results also showed that this was driven by a greater sensitivity to saturated fat, meaning that people at higher genetic risk had the largest increases in LDL cholesterol when they consumed more saturated fat. People following a low-fat diet did not show the same patterns.

Unlike prior studies, which have mostly focused on single genetic variants, researchers combined thousands of genetic variants across the genome (creating what is known as a polygenic score) to estimate each participant’s overall tendency for higher or lower LDL cholesterol. In the future, Barad said clinicians could potentially use polygenic scores to help identify people who are more likely to experience adverse LDL cholesterol responses to certain dietary modifications.

However, even without genetic testing, the study offers an important lesson that the response to diet can vary from person to person, underscoring the need to monitor how your body is responding to a dietary change rather than assuming the results will be the same for everyone, Barad added.

Further studies could help to confirm the findings and ensure they apply broadly to diverse populations. General dietary guidance suggests limiting saturated fat to less than 10% of daily calories and favoring unsaturated fats. For those choosing a low-carbohydrate diet, emphasizing healthier fat sources such as nuts, seeds, olive oil and avocado over foods high in saturated fat such as butter, beef tallow, fatty cuts of meat and processed meats may help reduce the risk of adverse cholesterol responses, Barad noted.