Study links ultra-processed foods to significantly higher prostate cancer risks

 Ultra-processed foods (UPFs) account for nearly 60% of adults’ and 70% of children’s energy intake in the United States. These industrially manufactured products – such as soft drinks, packaged cereals and snacks, and processed meats – are made with refined fats, oils, sugars, starches, salts and other additives that can enhance flavor, texture, and shelf life while reducing nutritional value.

Growing evidence links higher consumption of UPFs to a range of health problems. Research has identified several potential biological pathways through which UPFs may contribute to cancer. These include metabolic disruption, inflammation, oxidative stress, and changes to the gut microbiome. However, data are sparse about whether men who consume high amounts of UPFs have greater risks of prostate cancer.

Now, new research from Florida Atlantic University’s Charles E. Schmidt College of Medicine provides evidence that men with higher consumption of UPFs have increased risks of prostate cancer. In the U.S., prostate cancer is the most commonly diagnosed cancer and the second-leading cause of cancer death among men after lung cancer.

Published in The American Journal of Medicine, the study provides analyses from a large and nationally representative data from 17,024 U.S. men ages 18 and older who participated in the National Health and Nutrition Examination Survey (NHANES) from 2003 through 2023. Researchers used two 24-hour dietary recalls to calculate the percentage of daily calories participants consumed from UPFs. Using the validated and widely used NOVA classification system, they divided participants into four groups, ranging from less than about 20% of calories from UPFs to more than 44%.

Men in the three higher-consumption groups of UPFs had a 29% greater risk of prostate cancer, while those in the two highest-consumption groups had a 30% greater risk, compared to those in the lowest consumption group. After adjustments for age, race and ethnicity, smoking, and poverty status, the increased risk remained significant, ranging from 24% to 31%. Men with the highest UPF intake alone had a possible 34% higher risk, although the finding did not reach statistical significance, potentially reflecting the smaller number of prostate cancer cases in that group.

“Among adult men in this nationally representative U.S. population, those who consumed higher amounts of UPFs had significantly higher risks of the subsequent development of prostate cancer,” said Charles H. Hennekens, M.D., FACPM, FACC, senior author and the First Sir Richard Doll Professor of Medicine and Preventive Medicine in the Department of Medicine and the Department of Population Health at FAU’s College of Medicine. “These findings add to emerging evidence that UPFs have major adverse health effects and underscore the need for large-scale observational studies and randomized trials to adequately test the hypothesis.”

Previous studies have shown that people who consume larger amounts of UPFs have higher risks of overweight and obesity, metabolic disease, markers of inflammation, cardiovascular disease, principally heart attacks and strokes, as well as premature death.

This original research adds to the armamentaria of a major battle in which the priorities of the food  industry do not align with the needs of the U.S. public. The authors opine that just as the dangers of tobacco began to emerge during the middle of the prior century, decades passed before the preponderance of evidence and the efforts of forward-thinking health officials prompted policy changes to discourage cigarette use. The authors believe that this is likely to be a similar path for UPFs.

“Reducing consumption of UPFs is a complex public health challenge, particularly given how prevalent and accessible these products are,” said co-author Timothy De Ver Dye, Ph.D., professor and chair of FAU’s Department of Population Health. “Healthcare providers should recognize that many patients face barriers to accessing and affording healthier food options. Addressing these challenges will require efforts that extend beyond individual choices to support greater access to nutritious, minimally processed foods.”

Prostate cancer is a major health concern in the U.S. and worldwide. The American Cancer Society estimates that more than 333,000 men will be diagnosed with prostate cancer in the U.S. in 2026, with more than 36,000 expected to die from the disease. According to the International Agency for Research on Cancer, nearly 1.5 million men worldwide were diagnosed with prostate cancer in 2022, and nearly 400,000 died from the disease.

“All healthcare professionals should encourage patients to adopt healthy lifestyle practices and evidence-based therapies, while also helping them reduce their consumption of ultra-processed foods,” Hennekens said. “Patients and their healthcare providers should consider this finding as part of broader efforts to promote healthier dietary choices.”

Parents who run with a stroller have lower risk of overuse injury

 Anyone who has run while pushing a stroller knows stroller running can feel cumbersome and hard on the body. But does it increase the risk of injury? According to a new study from researchers at Penn State Berks, the answer appears to be no.

The study, published TODAY (Aug. 12) in the journal PLOS One, found that parents who ran with a stroller were less likely to sustain an overuse injury during the first three years after becoming a parent compared to those who ran without a stroller. For every 1,000 miles run, parents who ran with a stroller saw a 55% lower injury rate compared to those who ran without a stroller.

“This study is among the first to look at injury patterns in parents who run,” said senior author Allison Altman-Singles, associate professor of kinesiology and of mechanical engineering at Penn State Berks. “We saw that running with a stroller is safe and can help sustain physical activity during early parenthood.”

According to the researchers, previous studies have shown that running with a stroller alters the way a person runs. Stroller runners tend to have shorter strides, lean forward more, twist less through the torso and run slower. In this study, the researchers explored if and how running with a stroller influenced running habits and injury risk compared to running without a stroller.

The researchers recruited participants who had been a parent to children aged 0 to 3 within the last 20 years, who ran more than five miles per week before becoming a parent and who ran when their child was between six months and three years of age. Using a web-based survey, participants reported their running mileage from the time their child was born until age 10 and any injuries suffered during the first three years after becoming a parent.

The parents were then separated into two groups — those who ran regularly with a stroller and those who didn’t. The two groups were similar in age, height, weight, age when they had their first child and number of children. Most participants were female, particularly among the stroller running group.

Among 196 stroller runners and 53 non-stroller runners included in the final data analysis, 30% of those who ran without a stroller reported an overuse injury, compared to 19% of those in the stroller running group. The rate of injury for every 1,000 miles run was lower among stroller runners, too. Non-stroller runners were also more likely to experience multiple injuries during the first three years after becoming a parent.

“When you run with a stroller, you unweight the body a little bit, taking away some of the downward force by pressing on the handlebar, so you experience lower vertical loading,” Singles said. “This change in biomechanics may relieve some of the stress on weight-bearing joints, which may explain why we see fewer injuries among stroller runners, particularly knee injuries, which are common among runners.”

Prior research, led by Singles, found that running with a stroller decreases the force and impact of each step. The researchers explained that running with a stroller may also encourage parents to regulate their pace and run with a consistent cadence, or steps per minute — both of which are associated with lower injury risk, Singles said.

Both groups did report a high incidence of plantar fasciitis, a condition where the connective tissue along the bottom of the foot becomes inflamed, accounting for 15% of all reported injuries in the stroller-running group and 16% of all reported injuries in the non-stroller-running group. Given that most participants in both groups were women and were the birthing parent, Singles said that the incidence of plantar fasciitis may potentially be linked to physiological changes during pregnancy and the postpartum period, rather than the act of running with a stroller. For instance, factors like weight gain as well as hormonal shifts during pregnancy and the postpartum period, which can affect elasticity of connective tissues, could increase injury risk.

The study also tracked how running mileage changed based on a child’s age. Between birth and six months, neither group ran much, but by one year, both groups were running similar mileage. Stroller use peaked when children were between six months and three years old before declining as the child got older.

“The stroller also allowed people to run more when their child was between 6 and 12 months old,” Singles said, with stroller runners logging 34% more miles than non-stroller runners. “The stroller can help runners get out and exercise.”

The research team noted several limitations to the study including the relatively small study population for an injury study. The survey didn’t tease out factors that could potentially contribute to injury risk such as breastfeeding status and whether participants had additional children during the study period.

Taking the stairs could cut risk of early death

Taking the stairs will help you live longer - according to new research from the University of East Anglia and the Norfolk and Norwich University Hospital.

A major new study published today reveals that climbing the stairs significantly reduces the risk of dying from cardiovascular disease.

Over the course of the study, people who regularly climb stairs were 39 per cent less likely to die from heart-related problems and 24 per cent less likely to die from any cause - compared with people who don't climb stairs as often.

The study also reveals that people who climbed the stairs were less likely to develop major cardiovascular conditions such as heart attack, stroke and heart failure.

Prof Vassilios Vassiliou, from UEA’s Norwich Medical School, said: “Cardiovascular disease is the leading cause of death worldwide - with cases nearly doubling between 1990 and 2019.

“But it is largely preventable through a healthy lifestyle - including regular physical activity, a heart-healthy diet, not smoking, maintaining a healthy weight, and managing blood pressure, cholesterol, and diabetes.

“Taking the stairs is a practical and often overlooked way to build physical activity into daily life.

“We wanted to better understand how this everyday activity could have life-saving potential.”

Strong evidence from large-scale analysis

The research team investigated whether climbing stairs could play a role in reducing the risks of cardiovascular disease and premature death.

After reviewing nearly 1,900 studies, they analysed data from more than 480,000 participants across nine high quality studies with a median follow-up period of 14 years.

The study population included both healthy participants and those with a previous history of heart problems. Ages ranged from 35 to 84 years old and 53 per cent of participants were women.

Dr Sophie Paddock, also from UEA’s Norwich Medical School and a cardiology specialist registrar at the NNUH, said: “After pooling results from over 450,000 participants, we found a consistent association between stair climbing and lower risk of both cardiovascular death and overall mortality.

“Unlike going to the gym or doing a workout, climbing the stairs is something you can easily fit into your day at home, at work or when you're out. It's a good option for people who don't have much time or easy access to exercise.

“So if you have the choice of taking the stairs or the lift, go for the stairs as it will help your heart.

“Even brief bursts of physical activity have beneficial health impacts, and short bouts of stair climbing should be an achievable target to integrate into daily routines.”

Previous research cited in the study showed that just minutes of stair climbing several times a week can improve cardiorespiratory fitness and lower cholesterol.

One large cohort study included in the analysis suggested that climbing around six flights of stairs per day may deliver the greatest benefit, although researchers say the optimal “dose” requires further investigation.

Dr Paddock said: “Some of the studies we looked at showed that the more stairs climbed, the greater the health benefits. But even small changes had a measurable impact.”

A simple step forward

The findings reinforce broader evidence that even short bursts of physical activity can have meaningful health benefits.

Prof Vassiliou said: “With more than a quarter of adults worldwide failing to meet recommended activity levels, choosing to take the stairs offers a realistic, scalable intervention.

“Encouraging people to take the stairs in workplaces, public buildings and homes could form part of a wider strategy to reduce cardiovascular disease at population level.”

Not for everyone

While the benefits are clear, researchers caution that stair climbing may not be suitable for everyone - particularly those with mobility issues or joint conditions.

They also highlight the need for future research using wearable technology to measure activity more accurately and determine optimal recommendations.

‘Evaluating the Impact of Stair Climbing on Cardiovascular Risk Reduction: A Systematic Review and Meta-analysis’ is published in the American Journal of Cardiovascular Drugs.

Couples who exercise together report stronger communication and conflict resolution

Research has long shown that exercise benefits both physical and mental health. Now a new study from researchers at BYU suggests that it may also strengthen marriages, especially when couples exercise together.

The study, recently published in Family Relations, found that couples who participated in shared physical activity reported better communication, stronger conflict resolution and lower levels of marital stress than couples who did not exercise together.

The research was conducted by BYU School of Family Life professor Jeremy Yorgason alongside co-author Ashlyn Hiatt Mildenhall, who began the project as an undergraduate researcher at BYU.

“Our findings suggest that conjoint exercise facilitates, in a small but significant way, the ability to resolve conflict peacefully,” Yorgason said. “People reported more positive outcomes in communication and conflict resolution when they exercised together.”

Researchers analyzed survey data from nearly 1,700 young married couples participating in the nationally representative Couple Relationships and Transition Experiences (CREATE) study, a BYU project that has followed newly married couples across the United States for more than a decade.

The team compared the effects of individual workouts and physical activity performed together as a couple on three relationship outcomes: communication, conflict resolution and marital stress.

While both forms or exercise were associated with healthier marriages, exercising together consistently showed stronger associations with positive relationship outcomes than exercising alone.

“About 60% of husbands and wives in the sample said they exercised, but only about a third exercised together,” Yorgason said. “That means about half the people who exercise are not exercising with their spouse. While the impact is not necessarily large, it is very consistent, which gives me confidence that it is influencing relationships in some meaningful way.”

Other research shows that couples benefit from spending leisure time together, but this study focused specifically on shared physical activity. Researchers say exercising together likely created opportunities for positive interactions and conversation. These can strengthen relationships over time.

“Out of all three outcomes, exercise had the biggest impact on communication,” Mildenhall said. “That’s why it was interesting that walking was the number one reported exercise. It naturally provides opportunities to communicate.”

Walking was the most commonly reported form of shared exercise among couples in the study, suggesting that couples don’t need expensive gym memberships or elaborate weight racks in the garage to reap the potential relationship benefits.

Researchers also found that couples who exercised together reported better listening and greater feelings of being heard and supported by their spouse. Yorgason says these interactions may help explain why shared exercise was associated with healthier communication and conflict resolution.

The researchers caution that shared exercise is not a cure for relationship challenges. For many young couples, especially those raising children, exercising together may require intentionally carving out time together. However, researchers say conjoint exercise is one of the many healthy habits families can do to create regular opportunities for connection amid the demands of school, life and parenting.

Most patients with early Alzheimer’s disease not following guidelines for brain health

Researchers at the Mass General Brigham Neuroscience Institute found that most patients with early Alzheimer’s disease are not optimally adhering to recommendations for improving their brain health, including exercising, getting adequate sleep, preventing hypertension, and eating a heart-healthy diet. Results, published in The Journal of Prevention of Alzheimer’s Disease, show that fewer than 3% of the studied patients followed all 15 brain health recommendations the researchers examined. Both patients with early Alzheimer’s disease who pursued treatment with lecanemab, an anti-amyloid antibody medication for Alzheimer’s disease, and patients who did not pursue anti-amyloid therapy, had poor adherence to brain health recommendations, with no significant difference between those groups.

“Because patients pursuing anti-amyloid therapy were willing to receive lecanemab infusions every two weeks and tolerate the risks associated with this medication, we thought this highly motivated group might be pursuing every avenue available to protect their brain health,” said Kirk Daffner, MD, lead author of the study and a neurologist at the Mass General Brigham Neuroscience Institute. “The results show there is much more work to be done.”

Growing evidence links adequate physical activity, a healthy diet, sufficient sleep, social and cognitive engagement, controlled blood pressure and blood sugar, good vision and hearing, and low levels of alcohol consumption with a lower risk of cognitive decline and dementia. Brain Health Vital Signs, developed by Daffner, Seth Gale, MD, and colleagues, assesses 15 of these potentially modifiable factors to provide an overall brain health “score” and recommendations for improvement.

The researchers studied 150 patients with mild cognitive impairment or mild dementia due to Alzheimer’s disease who were seeking anti-amyloid antibody therapy and compared them with 117 patients with mild cognitive impairment or mild dementia who were not pursuing the therapy.

Among patients pursuing anti-amyloid therapy, more than 25% were not optimally adhering to 11 of the 15 studied brain health recommendations and more than 50% were not optimally adhering to four of the recommendations. Similar low adherence rates were observed in patients with early Alzheimer’s disease who did not pursue anti-amyloid therapy.

Patients most commonly fell short of the recommendation to get at least 25 minutes of physical activity per day on most days of the week (63% of patients pursuing anti-amyloid therapy did not meet this recommendation). Other especially challenging guidelines to meet included reducing stress and achieving low A1c levels, blood pressure and body mass index.

“There is a fairly robust, accepted evidence base that a certain set of behaviors and medical factors support brain health, but effective implementation in clinical care is still mostly missing,” said Seth Gale, MD, senior author and neurologist at the Mass General Brigham Neuroscience Institute. “While tools such as Brain Health Vital Signs can help patients and their providers better understand what they are doing well and where they can improve, it’s clear that structured, sustainable interventions are also necessary.”

The ongoing Brain Health Champion Study, led by Gale, Daffner and colleagues, with results from its first cohort of patients published in 2019, found that those who received six months of individualized brain health coaching markedly improved their adherence to recommended brain health behaviors. Daffner and Gale say that offering more effective tools to providers and their teams, grounded in health psychology-based techniques, may best help support behavior change in patients.

Nutrition strategies for concussion management

 Nutrition strategies for concussion management are being implemented by dietitians to support Australia’s elite collision sport athletes, new Griffith University research has found.

Lead author Dr Nathan Delang interviewed 14 Accredited Sports Dietitians who work across professional AFL, Rugby League, and Rugby Union teams to explore their practices and perspectives relating to concussion management.

“Concussion is so common in contemporary professional collision sports, typically once every three games, so it’s important to ensure optimal support is provided for athletes,” Dr Delang said.

“Most sports dietitians provided nutrition support either before and/or after concussion, with fish oil and creatine monohydrate the most commonly recommended supplements.

“Fish oil and creatine might support concussion recovery through several mechanisms from mitigating excessive neuroinflammation through to enhancing the availability of energy for supporting brain recovery and returning to exercise.

“All dietitians reported a food-first approach as central to recovery with a focus on energy intake, hydration, and healthy eating patterns to help athletes maintain their pre-injury nutrition status.”

Alongside fish oil and creatine, other supplements in use by professional teams included vitamin B2, tart cherry extract, curcumin, and vitamin D.

Professor Ben Desbrow from Griffith’s School of Allied Health, Sport and Social Work said while Australians sports dietitians were already using nutrition as part of concussion care, the practice was advancing faster than the evidence base.

“Practitioners are confident with familiar products, such as creatine, which are often already in use as a physical performance aid,” he said.

“However, they want stronger evidence so they can confidently tailor nutrition advice for complex concussion cases.

“We need stronger clinical research and formal guidelines to support safe, consistent and equitable care for athletes.”

The paper ‘Concussion and nutrition in professional-level collision sports: Perspectives from Australian Sports Dietitians’ has been published in The Journal of Nutrition.

Avoiding 3 risk factors associated with living 13 more years without dementia

 Highlights:

• Having normal blood pressure, no diabetes and not smoking was associated with living nearly 13 years longer without dementia.

• The study does not prove that avoiding these vascular risk factors causes the delay in dementia; it only shows an association.
• A limitation of the study was that the assessment of risk factors happened once, so it focused on long-term outcomes after one assessment, not changes in risk factors over time.

Having normal blood pressure, no diabetes and not smoking was associated with living nearly 13 years longer without dementia, according to a study published August 5, 2026, in Neurology® Open Access, an official journal of the American Academy of Neurology.

The study does not prove that avoiding these vascular risk factors causes the delay in dementia; it only shows an association.

“Our findings support prevention of risk factors developing in midlife as a strategy for delaying the onset of dementia and maintaining brain health,” said study author Josef Coresh, MD, PhD, of NYU Grossman School of Medicine in New York. “Finding ways to prevent or delay dementia is crucial as the population ages as treatments remain limited.”

The study involved 12,409 people with an average age of 56 who were free of dementia. People were assessed for three risk factors for dementia: high blood pressure, diabetes and smoking. High blood pressure was defined as blood pressure higher than 140/90 mmHg or the use of medication to lower blood pressure.

The participants were followed for an average of 26 years. During that time, 3,008 developed dementia and 5,238 people died without developing dementia.  

People who had none of the risk factors lived without developing dementia nearly 13 years longer than people with all three of the risk factors. People with no risk factors lived for an average of 30.1 years after the start of the study without dementia. People with all three risk factors lived for an average of 17.5 years without developing dementia.

Female participants lived longer than male participants without developing dementia, regardless of how many risk factors they had. Female participants with all three risk factors lived an average of 18.1 years without developing dementia, compared to 16.6 years for male participants.

Coresh noted, “Women more often reach older ages and therefore experience many cases of late-onset dementia.”

White participants lived longer than Black participants without developing dementia, no matter how many risk factors they had. White participants with all three risk factors lived an average of 19.6 years without developing dementia, compared to 16.0 years for Black participants.

“People with all three risk factors were more likely to develop dementia or die at earlier ages from other causes, leading to shorter overall survival and fewer years with their thinking and memory abilities intact,” Coresh said. “Hopefully these results will help encourage people to stop smoking, manage their blood sugar and manage their blood pressure in midlife. Of course, other healthy habits such as eating better and being more active are also important.”

A limitation of the study was that the assessment of risk factors happened once, so it focused on long-term outcomes after one assessment, not changes over time.