Friday, June 27, 2025

The latest addition to my supplements: TMG

 Also see 

1. https://healthnewsreport.blogspot.com/2025/01/recent-research-that-has-changed-ny-diet.html

2. https://healthnewsreport.blogspot.com/2024/05/my-supplements-updated.html


Betaine, also known as trimethylglycine (TMG), is a naturally occurring compound that has several important functions in the body. It's a modified amino acid, involved in methylation reactions and detoxification of homocysteine.  


Key Roles and Mechanisms:

  • Methyl Donor: Betaine serves as a methyl group donor, which is vital for various metabolic processes, including the conversion of homocysteine to methionine.
  • Homocysteine Metabolism: High levels of homocysteine are linked to increased risk of heart disease and stroke. Betaine helps lower these levels by converting homocysteine to methionine.
  • Osmoprotectant: Betaine helps regulate osmotic pressure within cells and tissues, crucial for maintaining cellular integrity.
  • Anti-inflammatory: Betaine has been shown to exhibit anti-inflammatory properties by inhibiting certain inflammatory pathways. 

Uses and Potential Benefits:

  • Homocystinuria Treatment: Betaine is used to treat homocystinuria, a genetic condition where the body cannot break down certain proteins, leading to homocysteine buildup.
  • Heart Health: By reducing homocysteine levels, betaine may contribute to heart health and potentially lower the risk of cardiovascular disease.
  • Liver Function: Studies suggest that betaine may support liver function and protect against liver damage.
  • Athletic Performance: Some research indicates that betaine supplementation might improve endurance, reduce fatigue, and enhance muscle power.
  • Digestive Health: Betaine hydrochloride (HCl) can be used as a supplement to support digestive function, particularly in individuals with low stomach acid.  

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