Key Points
Question What is the association between body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) in midlife and morbidity burden in older adulthood (≥65 years) and longevity?
Findings In this cohort study of 29 621 adults, being overweight and having classes I and II obesity compared with having a normal BMI at a mean age of 40 years were associated with a statistically significantly higher cumulative morbidity score and health care costs across older adulthood. Age at death was similar in the overweight and statistically significantly younger in the classes I and II obesity group compared with the normal BMI group.
Meaning This study’s findings suggest that overweight status beginning in midlife is associated with long-term adverse health and economic consequences in the context of similar longevity.
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