Monday, February 24, 2020

The highest probability of reaching 90 years was found for those drinking 5– < 15 g alcohol/day



For men: all drinks

For women: wine, not liquor

(In the United States, a standard drink contains about 14 grams of alcohol.[1] This corresponds to a 12-US-fluid-ounce (350 mL) glass of beer, a 5-US-fluid-ounce (150 mL) glass of 12% ABV (alcohol by volume) wine, or a 1.5-US-fluid-ounce (44 mL) so-called "shot" of spirit.[2] Assuming that beer is 5% ABV, wine is 12% ABV, and spirits is 40% ABV (80 proof). Most wine today is higher than 12% ABV (the average ABV in Napa Valley in 1971 was 12.5% [3]). 80 proof is still the standard for spirits, though higher alcohol content is common.)

Source: https://academic.oup.com/ageing/advance-article/doi/10.1093/ageing/afaa003/5730334#198738775



Background
whether light-to-moderate alcohol intake is related to reduced mortality remains a subject of intense research and controversy. There are very few studies available on alcohol and reaching longevity.
Methods
we investigated the relationship of alcohol drinking characteristics with the probability to reach 90 years of age. Analyses were conducted using data from the Netherlands Cohort Study. Participants born in 1916–1917 (n = 7,807) completed a questionnaire in 1986 (age 68–70 years) and were followed up for vital status until the age of 90 years (2006–07). Multivariable Cox regression analyses with fixed follow-up time were based on 5,479 participants with complete data to calculate risk ratios (RRs) of reaching longevity (age 90 years).
Results
we found statistically significant positive associations between baseline alcohol intake and the probability of reaching 90 years in both men and women. Overall, the highest probability of reaching 90 was found in those consuming 5– < 15 g/d alcohol, with RR = 1.36 (95% CI, 1.20–1.55) when compared with abstainers. 
United States[]14 g =1.4 standard drinks

The exposure-response relationship was significantly non-linear in women, but not in men. Wine intake was positively associated with longevity (notably in women), whereas liquor was positively associated with longevity in men and inversely in women. Binge drinking pointed towards an inverse relationship with longevity. Alcohol intake was associated with longevity in those without and with a history of selected diseases.
Conclusions
the highest probability of reaching 90 years was found for those drinking 5– < 15 g alcohol/day. Although not significant, the risk estimates also indicate to avoid binge drinking.

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