A new study, published today in Gut, spotlights vitamin B1 (thiamine) biology as an unexpected pathway for follow-up research. To explore whether this vitamin B1 signal shows up in real-world data, the researchers then turned to additional dietary information from UK Biobank. In 98,449 participants, they found that higher dietary thiamine intake was associated with more frequent bowel movements. Importantly, the relationship between thiamine intake and bowel movement frequency differed depending on a person’s genetic makeup at the SLC35F3 and XPR1 genes (analysed together as a combined genetic score). In other words, the data suggest that inherited differences in thiamine handling may influence how vitamin B1 intake relates to bowel habits in the general population.
- Whole & Fortified Grains: Enriched breads, cereals, pasta, brown rice, and wheat germ.
- Meats: Pork (especially), beef, liver, salmon.
- Legumes: Black beans, soybeans, peas.
- Nuts & Seeds: Sunflower seeds, flaxseeds, almonds, etc..
- Energy: Helps cells convert carbohydrates into usable energy.
- Nervous System: Essential for nerve signal conduction and overall nervous system health.
- Muscle Function: Aids in muscle contraction.
- Loss During Processing: Milling grains removes thiamine, so enrichment is common.
- Cooking: Some thiamine is lost during cooking.
- Thiaminase: Raw fish, shellfish, coffee, and tea contain enzymes that destroy thiamine.
- Deficiency (Beriberi): Can cause weakness, fatigue, confusion, and nerve damage, though rare with fortified foods.
- Supplements: Available as tablets or in B-complex/multivitamins
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