Analysis
finds strongest evidence of benefit in breast, colorectal cancers
Cancer
patients who have higher levels of vitamin D when they are diagnosed tend to
have better survival rates and remain in remission longer than patients who are
vitamin D-deficient, according to a new study published in the Endocrine
Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
The
body naturally produces vitamin D after exposure to sunlight and absorbs it
from certain foods. In addition to helping the body absorb the calcium and
phosphorus needed for healthy bones, vitamin D affects a variety of biological
processes by binding to a protein called a vitamin D receptor. This receptor is
present in nearly every cell in the body.
"By
reviewing studies that collectively examined vitamin D levels in 17,332 cancer
patients, our analysis demonstrated that vitamin D levels are linked to better
outcomes in several types of cancer," said one of the study's authors, Hui
Wang, MD, PhD, Professor of the Institute for Nutritional Sciences at the
Shanghai Institutes for Biological Sciences at the Chinese Academy of Sciences
in Shanghai, China. "The results suggest vitamin D may influence the
prognosis for people with breast cancer, colorectal cancer and lymphoma, in
particular."
The
meta-analysis looked at the results of 25 separate studies that measured
vitamin D levels in cancer patients at the time of diagnosis and tracked
survival rates. In most of the research, patients had their vitamin D levels
tested before they underwent any treatment for cancer. The study found a 10
nmol/L increase in vitamin D levels was tied to a 4 percent increase in
survival among people with cancer.
Researchers
found the strongest link between vitamin D levels and survival in breast
cancer, lymphoma and colorectal cancer. There was less evidence of a connection
in people with lung cancer, gastric cancer, prostate cancer, leukemia, melanoma
or Merkel cell carcinoma, but the available data were positive.
"Considering that vitamin D
deficiency is a widespread issue all over the world, it is important to ensure
that everyone has sufficient levels of this important nutrient," Wang
said. "Physicians need to pay close attention to vitamin D levels in
people who have been diagnosed with cancer."
No comments:
Post a Comment