A study of adults 40 and older
suggests high cholesterol levels are associated with increased risk for
the most common form of glaucoma, while longer use of a
cholesterol-lowering statin, compared with never using, was associated
with lower risk. Data for this observational study came from more than
136,000 adults who participated in three national study groups and
provided information on their statin use and cholesterol levels over 15
years. There were 886 new cases of primary open-angle glaucoma (POAG)
identified among the adults. The association between longer statin use
for five or more years and lower risk of POAG was stronger among those
65 and older. The study is limited by self-reported statin use and
cholesterol levels, and the results also may not generalize to other
groups because study participants were mostly white health care
professionals. These results need to be confirmed in other studies but
they are of interest given the widespread use of statins in older
persons at risk for this type of glaucoma.
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