JAMA Neurology
Bottom Line: Concussion is a common brain injury.
This observational study of nearly 29,000 adults (66 and older)
diagnosed with concussion examined whether statin use was associated
with risk of long-term dementia after a concussion. The analysis
compared 7,058 patients who received a statin prescription in the 90
days after a concussion with 21,757 who didn't. After an average
follow-up of four years, 4,727 patients developed dementia (1 in 6). The
risk of dementia in older adults after concussion was substantial, and
statin use was associated with modestly reduced risk compared to
patients who didn't receive a statin. Limitations of the study include
missing information on other factors that could influence the risk of
dementia.
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